Limited Competition: Development and Renovation of Research Space for HIV/AIDS Research at Institutions Serving Underrepresented Populations or Located in Institutional Development Award (IDeA)-eligible States (C06) | PAR 22 253

Opportunity Information: Apply for PAR 22 253

The National Institutes of Health (NIH) grant opportunity "Limited Competition: Development and Renovation of Research Space for HIV/AIDS Research at Institutions Serving Underrepresented Populations or Located in Institutional Development Award (IDeA)-eligible States (C06)" (Funding Opportunity Number PAR-22-253) is a discretionary grant program designed to help certain eligible institutions build, expand, or modernize physical research space dedicated to HIV/AIDS research. The main purpose is to strengthen the research infrastructure at institutions that either serve underrepresented and underserved populations or are located in IDeA-eligible states, where biomedical research capacity has historically been less well funded. The funded projects are specifically about facilities: creating or renovating research space so that investigators can conduct HIV/AIDS-related studies more effectively, safely, and at a higher level of competitiveness.

This FOA supports facility development and renovation that directly enables HIV/AIDS research across a broad range of scientific areas, including basic science, translational research, clinical research, and social and behavioral science research. The expectation is that the improved or newly created space will measurably support active and near-term HIV/AIDS research programs, not just general institutional growth. Applications must clearly tie the proposed construction or renovation to current research activities and to realistic, well-supported future needs. In other words, applicants have to make a convincing case that the space is necessary for the institution's HIV/AIDS research portfolio and that it will be used as intended by qualified research teams.

A key requirement is alignment with NIH-established priorities for HIV/AIDS research. That means the proposed facility work cannot be disconnected from NIH HIV/AIDS research goals; it must support research directions that NIH recognizes as priority areas. Applicants should be prepared to describe how the planned space will facilitate specific types of HIV/AIDS studies, the personnel and projects that will use the space, and how the facility improvements will remove barriers that currently limit productivity (for example, insufficient lab layout, lack of appropriate clinical research rooms, inadequate biosafety infrastructure, or insufficient space for community-engaged or behavioral research operations).

Eligibility is intentionally limited. The FOA is aimed at institutions that are not research-intensive; research-intensive institutions are explicitly not eligible. The program is structured to channel infrastructure investment toward places that typically have fewer large-scale capital resources, thereby expanding the geographic and demographic reach of HIV/AIDS research capacity. Eligible applicants span a wide range of organization types, including state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized tribal governments; tribal organizations that are not federally recognized; public housing authorities and Indian housing authorities; nonprofits (both 501(c)(3) and non-501(c)(3)); for-profit organizations other than small businesses; small businesses; and other eligible entities as allowed by NIH. The FOA also highlights several categories of institutions that are particularly relevant to its equity and capacity-building goals, such as Historically Black Colleges and Universities (HBCUs), Hispanic-serving institutions, Tribally Controlled Colleges and Universities (TCCUs), Alaska Native and Native Hawaiian Serving Institutions, and Asian American Native American Pacific Islander Serving Institutions (AANAPISIs), as well as faith-based or community-based organizations, eligible federal agencies, regional organizations, and U.S. territories or possessions.

At the same time, the FOA draws clear boundaries around foreign involvement. Non-domestic (non-U.S.) entities (foreign organizations and foreign institutions) are not eligible to apply. In addition, non-domestic components of U.S. organizations are not eligible, and foreign components, as defined by the NIH Grants Policy Statement, are not allowed. In practice, this means the facility work and the supported research environment must be fully domestic and not depend on foreign subcomponents.

Administratively, this is an NIH-funded grant mechanism in the health area (CFDA number 93.352), with the opportunity created on October 11, 2022, and an original closing date listed as January 7, 2023. The announcement is framed as a limited competition, which typically means eligibility is constrained by design and may involve additional NIH institute or center-specific rules, priorities, or selection constraints beyond what is typical for fully open solicitations. The award ceiling and expected number of awards are not specified in the provided source information, so applicants would normally need to consult the full FOA text and related NIH guidance to understand budget limits, allowable and unallowable costs, project period expectations, and any cost-sharing or matching requirements that may apply under the C06 construction/renovation mechanism.

Overall, this opportunity is best understood as an infrastructure investment program tied directly to HIV/AIDS scientific priorities and equity-driven capacity building. The core idea is straightforward: fund renovation or development of research space at eligible, non-research-intensive institutions so they can conduct NIH-priority HIV/AIDS research more effectively, expand participation of underrepresented and underserved communities in the research ecosystem, and strengthen the long-term ability of these institutions to compete for and carry out impactful HIV/AIDS research.

• The National Institutes of Health in the health sector is offering a public funding opportunity titled "Limited Competition: Development and Renovation of Research Space for HIV/AIDS Research at Institutions Serving Underrepresented Populations or Located in Institutional Development Award (IDeA)-eligible States (C06)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.352.
• This funding opportunity was created on 2022-10-11.
• Applicants must submit their applications by 2023-01-07. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

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